Type III secretion system genes in clinical Aeromonas isolates.
نویسندگان
چکیده
We have identified the genes ascF and ascG, which encode components of a putative type III secretion system (TTSS) in AEROMONAS: We investigated the distribution of these and other TTSS genes in 84 clinical isolates and found hybridizing sequences in 50% of the strains, with a higher prevalence in Aeromonas hydrophila and Aeromonas veronii than in Aeromonas caviae.
منابع مشابه
فراوانی ژن‌های کد کننده سیتوتوکسین‌های exoT، exoY، exoS وexoU سیستم ترشحی تیپ 3 در سودوموناس آئروجینوزا جدا شده از بیماران سوختگی
Background and Objective: Pseudomonas aeruginosa is an opportunistic pathogen causing nosocomial burn infections. Disease results from the production of numerous virulence factors, some of which are injected directly into the eukaryotic host cells via the type III secretion system (T3SS).The aim of this study was to determine the prevalence of cytotoxins encoding exoT, exoY, exoS and exoU genes...
متن کاملMolecular Investigation of Outer Membrane Channel Genes Among Multidrug Resistance Clinical Pseudomonas Aeruginosa Isolates
Background: Multidrug resistance Pseudomonas aeruginosa (MDRPA) is most important issue in healthcare setting. It can secrete many virulence effector proteins via its secretion system type (T1SS-T6SS). They are using them as conductor for delivering the effector proteins outside to begins harmful effect on host cell increasing pathogenicity, competition against other microorganism and nutrient ...
متن کاملویژگیهای سیستم ترشحی نوع 3 در نمونه‌های سودوموناس ائروژینوزای جدا شده از بیماران مبتلا به سیستیک فیبروزیس
Abstract Background: Pseudomonas aeruginosalung infection is a major cause of morbidity and mortality in patients with cystic fibrosis (CF). The type III secretion system is an important and identified virulence determinant of P. aeruginosa that delivers effector proteins into targeted host cells. Three effector proteins have been described in P. aeruginosa: exoS, exoT, exoU. Unlike many studie...
متن کاملType III secretion genes in Aeromonas salmonicida subsp salmonicida are located on a large thermolabile virulence plasmid.
Type III secretion genes in Aeromonas salmonicida subsp. salmonicida are located on a large plasmid of approximately 140 kb. Cultivation of this organism at elevated temperatures such as 25 degrees C can, however, result in loss of this plasmid. This is accompanied by a loss of virulence for cultured fish cells.
متن کاملComplete type III secretion system of a mesophilic Aeromonas hydrophila strain.
We have investigated the existence and genetic organization of a functional type III secretion system (TTSS) in a mesophilic Aeromonas strain by initially using the Aeromonas hydrophila strain AH-3. We report for the first time the complete TTSS DNA sequence of an Aeromonas strain that comprises 35 genes organized in a similar disposition as that in Pseudomonas aeruginosa. Using several gene pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of clinical microbiology
دوره 42 3 شماره
صفحات -
تاریخ انتشار 2004